Gene description for HSPA4
Gene name	heat shock protein family A (Hsp70) member 4
Gene symbol	HSPA4
Other names/aliases	APG-2 HEL-S-5a HS24/P52 HSPH2 RY hsp70 hsp70RY
Species	Homo sapiens
Experiment description of studies that identified HSPA4 in Malignant pleural effusions
1 Experiment ID 109 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 21601258    Organism Homo sapiens Experiment description Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Authors Rupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P. Journal name GO Publication year 2011 Sample Malignant pleural effusions Sample name Pleural effusions - breast cancer Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (EpCAM) Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%
2 Experiment ID 519 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Ectosomes/Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 23585444    Organism Homo sapiens Experiment description Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Authors Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. Journal name Proteomics Publication year 2013 Sample Malignant pleural effusions Sample name Non-small cell lung cancer patient-Lung cancer pleural effusion Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130049: EV-METRIC:38%